VDAC1 Antibody

CATALOG NUMBER: 28-243

Clonality:
Polyclonal
Tested Applications:
ELISA, IHC, WB
Host Species:
Rabbit
Species Reactivity:
Dog, Human, Mouse, Rat
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Dog, Human, Mouse, Rat
Immunogen:
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human VDAC1.
Conjugate:
Unconjugated
Tested Applications:
ELISA, IHC, WB
Application Note:
VDAC1 antibody can be used for detection of VDAC1 by ELISA at 1:312500. VDAC1 antibody can be used for detection of VDAC1 by western blot at 1.25 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Positive Control 1:
Cat. No. 1211 - HepG2 Cell Lysate
Predicted Molecular Weight:
31 kDa
Purification:
Antibody is purified by protein A chromatography method.
Clonality:
Polyclonal
physical-state:
Liquid
Buffer:
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Concentration:
batch dependent
Storage Conditions:
For short periods of storage (days) store at 4°C. For longer periods of storage, store VDAC1 antibody at -20°C. As with any antibody avoid repeat freeze-thaw cycles.
Ncbi Official Symbol:
VDAC1
Additional Names:
VDAC1, PORIN, VDAC-1
Protein Accession Number:
NP_003365
Protein Gi Number:
4507879
Ncbi Gene Id Number:
7416
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
The voltage-dependent anion-selective channel 1 (VDAC1) functions as a channel in membranous structures for the outer mitochondrial membrane, the cell membrane, endosomes, caveolae, the sarcoplasmatic reticulum, synaptosomes, and post-synaptic density fraction. A major function of VDAC1 in the plasma membrane is that of a NADH (-ferricyanide) reductase that may be involved in the maintenance of cellular redox homeostasis.
Background Reference 1:
Zheng, Y., et al., (2004) Oncogene 23 (6), 1239-1247.

FOR RESEARCH USE ONLY

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Disclaimer:
This product is for research use only.

CATALOG NUMBER:

28-243

List Size:
100 ul

List Price:

$473.00

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