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Western blot analysis in HL-60 cell line lysates (35ug/lane).
Western blot analysis in HL-60 cell line lysates (35ug/lane).

VDR Antibody

CATALOG NUMBER: 59-872

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Immunogen:
This VDR antibody is generated from rabbits immunized with a recombinant protein of human VDR.
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
For WB starting dilution is: 1:1000
Predicted Molecular Weight:
48 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
Physical State:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
VDR
Additional Names:
Vitamin D3 receptor, VDR,25-dihydroxyvitamin D3 receptor, Nuclear receptor subfamily 1 group I member 1, VDR, NR1I1
Protein Accession Number:
P11473
Protein Gi Number:
137617
Ncbi Gene Id Number:
7421
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
This gene encodes the nuclear hormone receptor for vitaminD3. This receptor also functions as a receptor for the secondarybile acid lithocholic acid. The receptor belongs to the family oftrans-acting transcriptional regulatory factors and shows sequencesimilarity to the steroid and thyroid hormone receptors. Downstreamtargets of this nuclear hormone receptor are principally involvedin mineral metabolism though the receptor regulates a variety ofother metabolic pathways, such as those involved in the immuneresponse and cancer. Mutations in this gene are associated withtype II vitamin D-resistant rickets. A single nucleotidepolymorphism in the initiation codon results in an alternatetranslation start site three codons downstream. Alternativesplicing results in multiple transcript variants encoding the sameprotein.
Background Reference 1:
An, B.S., et al. Mol. Cell. Biol. 30(20):4890-4900(2010)
Background Reference 2:
Elnenaei, M.O., et al. Br. J. Nutr., 1-8 (2010) In press :
Background Reference 3:
Forghani, N., et al. J. Pediatr. Endocrinol. Metab. 23(8):843-850(2010)
Background Reference 4:
Alvarez-Nava, F., et al. J. Pediatr. Endocrinol. Metab. 23(8):773-782(2010)

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

59-872

List Size:
400 ul

List Price:

$495.00

Datasheet
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