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Western blot analysis of lysed extracts from HT29 cells untreated or treated with SCF-1 using VEGFR2 (phospho-Tyr1059).
Western blot analysis of lysed extracts from HT29 cells untreated or treated with SCF-1 using VEGFR2 (phospho-Tyr1059).

VEGFR2 (phospho Tyr1059) Antibody

CATALOG NUMBER: 79-507

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Rabbit
Species Reactivity:
Human, Mouse
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human, Mouse
Immunogen:
VEGFR2 (phospho-Tyr1059) antibody was raised against a peptide sequence around phosphorylation site of tyrosine 1059 (P-D-Y (p) -V-R) derived from Human VEGFR2.
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
Western Blot: 1:1000
Specificity:
This antibody detects endogenous level of VEGFR2 only when phosphorylated at Tyrosine 1059.
Predicted Molecular Weight:
230 kDa
Purification:
Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide.
Clonality:
Polyclonal
Physical State:
Liquid
Buffer:
Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration:
1 mg/mL
Storage Conditions:
Store antibody at -20°C for up to one year.
Ncbi Official Symbol:
KDR
Additional Names:
FLK1, CD309, VEGFR, VEGFR2, AMPK1, FLK1, KDR
Protein Accession Number:
NP_002244.1
Protein Gi Number:
11321597
Ncbi Gene Id Number:
3791
Background:
Receptor for VEGF or VEGFC. Has a tyrosine-protein kinase activity. The VEGF-kinase ligand/receptor signaling system plays a key role in vascular development and regulation of vascular permeability. In case of HIV-1 infection, the interaction with extracellular viral Tat protein seems to enhance angiogenesis in Kaposi's sarcoma lesions
Background Reference 1:
Zeng H, et al. (2001) J Biol Chem. 276 (35): 32714-32719. Dougher M, et al. (1999) Oncogene. 18 (8): 1619-1627.

FOR RESEARCH USE ONLY

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Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

79-507

List Size:
0.1 mg

List Price:

$376.00

Datasheet
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