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Western blot analysis of extracts from HT29 cells treated with Heatshock using Phospho-Vitamin D Receptor (Ser208) Antibody. The lane on the right is treated with the antigen-specific peptide.
Western blot analysis of extracts from HT29 cells treated with Heatshock using Phospho-Vitamin D Receptor (Ser208) Antibody. The lane on the right is treated with the antigen-specific peptide.

Vitamin D Receptor (phospho Ser208) Antibody

CATALOG NUMBER: 80-042

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Immunogen:
Vitamin D Receptor (phospho Ser208) antibody was raised against a peptide sequence around phosphorylation site of serine 208 (A-L-S (p)-P-V) derived from Human Vitamin D Receptor.
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
Western Blot: 1:500~1:1000
Specificity:
The antibody detects endogenous level of Vitamin D Receptor only when phosphorylated at serine 208.
Predicted Molecular Weight:
55 kDa
Purification:
Antibodies were purified by affinity-chromatography using epitope-specific peptide.
Clonality:
Polyclonal
Isotype:
IgG
Physical State:
Liquid
Buffer:
Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration:
1 mg/mL
Storage Conditions:
Store antibody at -20°C for up to one year.
Ncbi Official Symbol:
VDR
Additional Names:
NR1I1, vitamin D receptor, vitamin D3 receptor
Protein Accession Number:
NP_000367.1
Protein Gi Number:
4507883
Ncbi Gene Id Number:
7421
Background:
Nuclear hormone receptor. Transcription factor that mediates the action of vitamin D3 by controlling the expression of hormone sensitive genes. Regulates transcription of hormone sensitive genes via its association with the WINAC complex, a chromatin-remodeling complex. Recruited to promoters via its interaction with the WINAC complex subunit BAZ1B/WSTF, which mediates the interaction with acetylated histones, an essential step for VDR-promoter association. Plays a central role in calcium homeostasis.
Background Reference 1:
Arriagada G, et al. (2007) J Steroid Biochem Mol Biol 103, 425-9. Jurutka PW, et al. (1996)Proc Natl Acad Sci U S A 93, 3519-24. Jurutka PW, et al. (1993)J Biol Chem 268, 6791-9.

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

80-042

List Size:
0.1 mg

List Price:

$325.00

Out of stock

Datasheet
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