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Western blot analysis in K562 cell line lysates (35ug/lane).
Western blot analysis in K562 cell line lysates (35ug/lane).

VPS11 Antibody

CATALOG NUMBER: 58-530

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Homology:
Predicted species reactivity based on immunogen sequence: Mouse
Immunogen:
This VPS11 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 772-800 amino acids from the C-terminal region of human VPS11.
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
For WB starting dilution is: 1:1000
Predicted Molecular Weight:
108 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
Physical State:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
VPS11
Additional Names:
Vacuolar protein sorting-associated protein 11 homolog, hVPS11, RING finger protein 108, VPS11, RNF108
Protein Accession Number:
Q9H270
Protein Gi Number:
23396928
Ncbi Gene Id Number:
55823
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
Vesicle mediated protein sorting plays an important rolein segregation of intracellular molecules into distinct organelles.Genetic studies in yeast have identified more than 40 vacuolarprotein sorting (VPS) genes involved in vesicle transport tovacuoles. This gene encodes the human homolog of yeast class CVps11 protein. The mammalian class C Vps proteins are predominantlyassociated with late endosomes/lysosomes, and like their yeastcounterparts, may mediate vesicle trafficking steps in theendosome/lysosome pathway.
Background Reference 1:
Bailey, S.D., et al. Diabetes Care (2010) In press :
Background Reference 2:
Talmud, P.J., et al. Am. J. Hum. Genet. 85(5):628-642(2009)
Background Reference 3:
Zhu, G.D., et al. Mol. Biol. Cell 20(4):1223-1240(2009)
Background Reference 4:
Wan, D., et al. Proc. Natl. Acad. Sci. U.S.A. 101(44):15724-15729(2004)

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

58-530

List Size:
400 ul

List Price:

$495.00

Datasheet
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