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Western blot analysis in Jurkat cell line lysates (35ug/lane).
Western blot analysis in Jurkat cell line lysates (35ug/lane).

VPS4B Antibody

CATALOG NUMBER: 57-287

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Immunogen:
This VPS4B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 304-332 amino acids from the C-terminal region of human VPS4B.
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
For WB starting dilution is: 1:1000
Predicted Molecular Weight:
49 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
Physical State:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
VPS4B
Additional Names:
Vacuolar protein sorting-associated protein 4B, Cell migration-inducing gene 1 protein, Suppressor of K(+) transport growth defect 1, Protein SKD1, VPS4B, SKD1, VPS42
Protein Accession Number:
O75351
Ncbi Gene Id Number:
9525
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
The protein encoded by this gene is a member of the AAAprotein family (ATPases associated with diverse cellularactivities), and is the homolog of the yeast Vps4 protein. Inhumans, two paralogs of the yeast protein have been identified. Theformer share a high degree of aa sequence similarity with eachother, and also with yeast Vps4 and mouse Skd1 proteins. Mouse Skd1(suppressor of K+ transport defect 1) has been shown to be a yeastVps4 ortholog. Functional studies indicate that both human paralogsassociate with the endosomal compartments, and are involved inintracellular protein trafficking, similar to Vps4 protein inyeast. The gene encoding this paralog has been mapped to chromosome18; the gene for the other resides on chromosome 16. [provided byRefSeq].
Background Reference 1:
Morita, E., et al. Proc. Natl. Acad. Sci. U.S.A. 107(29):12889-12894(2010)
Background Reference 2:
McDonough, C.W., et al. Hum. Genet. (2009) In press :
Background Reference 3:
Bruce, E.A., et al. Virology 390(2):268-278(2009)
Background Reference 4:
Inoue, M., et al. Traffic 9(12):2180-2189(2008)

FOR RESEARCH USE ONLY

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Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

57-287

List Size:
400 ul

List Price:

$495.00

Datasheet
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