WASP Antibody

CATALOG NUMBER: 79-733

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Rabbit
Species Reactivity:
Human, Mouse, Rat
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human, Mouse, Rat
Immunogen:
WASP antibody was raised against a peptide sequence around aa.289~293 (L-I-Y-D-F) derived from Human WASP.
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
Western Blot: 1:500~1:1000
Specificity:
This antibody detects endogenous level of total WASP protein.
Predicted Molecular Weight:
53 kDa
Purification:
Antibodies were purified by affinity-chromatography using epitope-specific peptide.
Clonality:
Polyclonal
Physical State:
Liquid
Buffer:
Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration:
1 mg/mL
Storage Conditions:
Store antibody at -20°C for up to one year.
Ncbi Official Symbol:
WAS
Additional Names:
THC, IMD2, SCNX, THC1, WASP, THC
Protein Accession Number:
NP_000368.1
Protein Gi Number:
4507909
Ncbi Gene Id Number:
7454
Background:
Effector protein for Rho-type GTPases. Regulates actin filament reorganization via its interaction with the Arp2/3 complex. Important for efficient actin polymerization. Possible regulator of lymphocyte and platelet function. Mediates actin filament reorganization and the formation of actin pedestals upon infection by pathogenic bacteria.
Background Reference 1:
Kolluri R., Tolias K. F., Carpenter C. L., Rosen F. S., Kirchhausen T. Proc. Natl. Acad. Sci. U. S. A. 93:5615-5618 (1996) Ramesh N., Anton I. M., Hartwig J. H., Geha R. S. Proc. Natl. Acad. Sci. U. S. A. 94:14671-14676 (1997) Cory G. O. C., Cramer R., Blanchoin L., Ridley A. J. Mol. Cell 11:1229-1239 (2003)

FOR RESEARCH USE ONLY

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Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

79-733

List Size:
0.1 mg

List Price:

$370.00

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