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Western blot analysis in HepG2 cell line lysates (35ug/lane).
WDR12 Antibody immunohistochemistry analysis in formalin fixed and paraffin embedded human pancreas tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.
Western blot analysis in HepG2 cell line lysates (35ug/lane).

WDR12 Antibody

CATALOG NUMBER: 56-836

Clonality:
Polyclonal
Tested Applications:
IHC-P, WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Homology:
Predicted species reactivity based on immunogen sequence: Bovine
Immunogen:
This WDR12 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 210-239 amino acids from the Central region of human WDR12.
Conjugate:
Unconjugated
Tested Applications:
IHC-P, WB
Application Note:
For WB starting dilution is: 1:1000
For IHC-P starting dilution is: 1:10~50
Predicted Molecular Weight:
48 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
Physical State:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
WDR12
Additional Names:
Ribosome biogenesis protein WDR12 {ECO:0000255, HAMAP-Rule:MF_03029}, WD repeat-containing protein 12 {ECO:0000255, HAMAP-Rule:MF_03029}, WDR12 {ECO:0000255, HAMAP-Rule:MF_03029}
Protein Accession Number:
Q9GZL7
Protein Gi Number:
20140802
Ncbi Gene Id Number:
55759
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
This gene encodes a member of the WD repeat proteinfamily. WD repeats are minimally conserved regions of approximately40 amino acids typically bracketed by gly-his and trp-asp (GH-WD),which may facilitate formation of heterotrimeric or multiproteincomplexes. Members of this family are involved in a variety ofcellular processes, including cell cycle progression, signaltransduction, apoptosis, and gene regulation. This protein ishighly similar to the mouse WD repeat domain 12 protein at theamino acid level. The protein encoded by this gene is a componentof a nucleolar protein complex that affects maturation of the largeribosomal subunit.
Background Reference 1:
Kathiresan, S., et al. Nat. Genet. 41(3):334-341(2009)
Background Reference 2:
Rohrmoser, M., et al. Mol. Cell. Biol. 27(10):3682-3694(2007)
Background Reference 3:
Higa, L.A., et al. Nat. Cell Biol. 8(11):1277-1283(2006)
Background Reference 4:
Grimm, T., et al. Nucleic Acids Res. 34(10):3030-3043(2006)

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

56-836

List Size:
400 ul

List Price:

$495.00

Datasheet
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