WDR39 Antibody

CATALOG NUMBER: 28-080

Clonality:
Polyclonal
Tested Applications:
ELISA, WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Immunogen:
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human WDR39.
Conjugate:
Unconjugated
Tested Applications:
ELISA, WB
Application Note:
WDR39 antibody can be used for detection of WDR39 by ELISA at 1:62500. WDR39 antibody can be used for detection of WDR39 by western blot at 2.5 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Positive Control 1:
Cat. No. 1205 - Jurkat Cell Lysate
Predicted Molecular Weight:
38 kDa
Purification:
Antibody is purified by protein A chromatography method.
Clonality:
Polyclonal
Physical State:
Liquid
Buffer:
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Concentration:
batch dependent
Storage Conditions:
For short periods of storage (days) store at 4°C. For longer periods of storage, store WDR39 antibody at -20°C. As with any antibody avoid repeat freeze-thaw cycles.
Ncbi Official Symbol:
CIAO1
Additional Names:
WDR39, CIAO1, CIA1, WDR39
Protein Accession Number:
NP_004795
Protein Gi Number:
4757988
Ncbi Gene Id Number:
9391
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
WDR39 is a member of the WD40 family of proteins. WDR39 specifically interacts with WT1 both in vitro and in vivo. This interaction results in a decrease in transcriptional activation mediated by WT1. WDR39 does not inhibit binding of WT1 to its consensus nucleotide sequence and does not affect the repression activity of WT1. Thus, WDR39 appears to specifically modulate the transactivation activity of WT1 and may function to regulate the physiological functions of WT1 in cell growth and differentiation.
Background Reference 1:
Johnstone, R.W., (1998) J. Biol. Chem. 273 (18), 10880-10887.

FOR RESEARCH USE ONLY

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Disclaimer:
This product is for research use only.

CATALOG NUMBER:

28-080

List Size:
100 ul

List Price:

$473.00

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