WDR45 Antibody

CATALOG NUMBER: 56-982

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Homology:
Predicted species reactivity based on immunogen sequence: Zebrafish, Mouse, Rat
Immunogen:
This WDR45 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 17-46 amino acids from the N-terminal region of human WDR45.
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
For WB starting dilution is: 1:1000
Predicted Molecular Weight:
40 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
Physical State:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
WDR45
Additional Names:
WD repeat domain phosphoinositide-interacting protein 4, WIPI-4, WD repeat-containing protein 45, WDR45, WDRX1, WDRXI4, WIPI4
Protein Accession Number:
Q9Y484
Protein Gi Number:
74762056
Ncbi Gene Id Number:
11152
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
This gene encodes a member of the WD repeat proteinfamily. WD repeats are minimally conserved regions of approximately40 amino acids typically bracketed by gly-his and trp-asp (GH-WD),which may facilitate formation of heterotrimeric or multiproteincomplexes. Members of this family are involved in a variety ofcellular processes, including cell cycle progression, signaltransduction, apoptosis, and gene regulation. This gene has apseudogene at chromosome 4q31.3. Multiple alternatively splicedtranscript variants encoding distinct isoforms have been found forthis gene, but the biological validity and full-length nature ofsome variants have not been determined.
Background Reference 1:
Proikas-Cezanne, T., et al. Oncogene 23(58):9314-9325(2004)
Background Reference 2:
Jeffries, T.R., et al. Mol. Biol. Cell 15(6):2652-2663(2004)
Background Reference 3:
Clark, A.G., et al. Science 302(5652):1960-1963(2003)

FOR RESEARCH USE ONLY

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Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

56-982

List Size:
400 ul

List Price:

$495.00

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