XCR1 Antibody

CATALOG NUMBER: 56-196

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Immunogen:
This XCR1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 305-333 amino acids from the C-terminal region of human XCR1.
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
For WB starting dilution is: 1:1000
Predicted Molecular Weight:
39 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
Physical State:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
XCR1
Additional Names:
Chemokine XC receptor 1, G-protein coupled receptor 5, Lymphotactin receptor, XC chemokine receptor 1, XCR1, CCXCR1, GPR5
Protein Accession Number:
P46094
Protein Gi Number:
1170008
Ncbi Gene Id Number:
2829
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
The protein encoded by this gene is a chemokine receptorbelonging to the G protein-coupled receptor superfamily. The familymembers are characterized by the presence of 7 transmembranedomains and numerous conserved amino acids. This receptor is mostclosely related to RBS11 and the MIP1-alpha/RANTES receptor. Ittransduces a signal by increasing the intracellular calcium ionslevel. The viral macrophage inflammatory protein-II is anantagonist of this receptor and blocks signaling. Two alternativelyspliced transcript variants encoding the same protein have beenfound for this gene.
Background Reference 1:
Yamazaki, C., et al. Biochem. Biophys. Res. Commun. 397(4):756-761(2010)
Background Reference 2:
Crozat, K., et al. J. Exp. Med. 207(6):1283-1292(2010)
Background Reference 3:
Bachem, A., et al. J. Exp. Med. 207(6):1273-1281(2010)
Background Reference 4:
Davila, S., et al. Genes Immun. 11(3):232-238(2010)

FOR RESEARCH USE ONLY

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Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

56-196

List Size:
400 ul

List Price:

$495.00

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