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Western Blot at 1:2000 dilution Lane 1: Hela whole cell lysate Lane 2: MCF-7 whole cell lysate Lane 3: ZR-75-1 whole cell lysate Lysates/proteins at 20 ug per lane.
Western Blot at 1:2000 dilution Lane 1: Hela whole cell lysate Lane 2: MCF-7 whole cell lysate Lane 3: ZR-75-1 whole cell lysate Lysates/proteins at 20 ug per lane.

XPC Antibody

CATALOG NUMBER: 60-674

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Immunogen:
This XPC antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 154-183 amino acids from the N-terminal region of human XPC.
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
For WB starting dilution is: 1:2000
Predicted Molecular Weight:
106 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
Physical State:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
XPC
Additional Names:
DNA repair protein complementing XP-C cells, Xeroderma pigmentosum group C-complementing protein, p125, XPC, XPCC
Protein Accession Number:
Q01831
Protein Gi Number:
296453081
Ncbi Gene Id Number:
7508
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
This gene encodes a component of the nucleotide excisionrepair (NER) pathway. There are multiple components involved in theNER pathway, including Xeroderma pigmentosum (XP) A-G and V,Cockayne syndrome (CS) A and B, and trichothiodystrophy (TTD) groupA, etc. This component, XPC, plays an important role in the earlysteps of global genome NER, especially in damage recognition, opencomplex formation, and repair protein complex formation. Mutationsin this gene or some other NER components result in Xerodermapigmentosum, a rare autosomal recessive disorder characterized byincreased sensitivity to sunlight with the development ofcarcinomas at an early age. Alternatively spliced transcriptvariants have been found for this gene.
Background Reference 1:
Gangwar, R., et al. J. Cancer Res. Clin. Oncol. (2009) In press :
Background Reference 2:
Agalliu, I., et al. Cancer Causes Control (2009) In press :
Background Reference 3:
Langie, S.A., et al. Br. J. Nutr., 1-12 (2009) In press :
Background Reference 4:
Young, R.P., et al. Postgrad Med85(1008):515-524(2009)

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

60-674

List Size:
400 ul

List Price:

$495.00

Datasheet
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