XRCC3 Antibody

CATALOG NUMBER: XW-7922

Clonality:
Polyclonal
Tested Applications:
ELISA, WB
Host Species:
Chicken
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Chicken
Species Reactivity:
Human
Immunogen:
213-346
Conjugate:
Unconjugated
Tested Applications:
ELISA, WB
Application Note:
XRCC3 antibody can be used for the detection of DNA-repair protein XRCC3 by ELISA and Western Blot, may also work for ICC and IHC.
Predicted Molecular Weight:
37.9 kDa (calculated)
Purification:
Immunoaffinity Purified
Clonality:
Polyclonal
Physical State:
Liquid
Buffer:
Phosphate-Buffered Saline. No preservatives added.
Concentration:
1 mg/mL
Storage Conditions:
XRCC3 antibody can be stored at 4°C for short term (weeks). Long term storage should be at -20°C. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
XRCC3
Additional Names:
DNA repair protein XRCC3, X-ray repair cross-complementing protein 3, CMM6
Protein Accession Number:
NP_005423.1
Protein Gi Number:
4885659
Ncbi Gene Id Number:
7517
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
This protein is a member of the RecA/Rad51-related protein family that participates in homologous recombination to maintain chromosome stability and repair DNA damage. This protein functionally complements Chinese hamster irs1SF, a repair-deficient mutant that exhibits hypersensitivity to a number of different DNA-damaging agents and is chromosomally unstable. A rare microsatellite polymorphism in this gene is associated with cancer in patients of varying radiosensitivity.

FUNCTION: Involved in the homologous recombination repair (HRR) pathway of double-stranded DNA, thought to repair chromosomal fragmentation, translocations and deletions.

DISEASE: Met-241 is associated with the development of cutaneous malignant melanoma.

SUBUNIT: Interacts with RAD51C and RAD51. Part of a complex consisting of RAD51B, RAD51C, RAD51D, XRCC2 and XRCC3.

SIMILARITY: Belongs to the recA family. RAD51 subfamily.

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

XW-7922

List Size:
0.05 mg

List Price:

$565.00

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