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Western blot analysis in T47D cell line lysates (35ug/lane).
Western blot analysis in T47D cell line lysates (35ug/lane).

XRN2 Antibody

CATALOG NUMBER: 57-673

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Homology:
Predicted species reactivity based on immunogen sequence: Chicken, Drosophila, Mouse
Immunogen:
This XRN2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 48-76 amino acids from the N-terminal region of human XRN2.
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
For WB starting dilution is: 1:1000
Predicted Molecular Weight:
109 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
physical-state:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
XRN2
Additional Names:
5'-3' exoribonuclease 2, 3113-, DHM1-like protein, DHP protein, XRN2
Protein Accession Number:
Q9H0D6
Protein Gi Number:
30173484
Ncbi Gene Id Number:
22803
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
This gene shares similarity with the mouse Dhm1 and theyeast dhp1 gene. The yeast gene is involved in homologousrecombination and RNA metabolism, such as RNA synthesis and RNAtrafficking. Complementation studies show that Dhm1 has a similarfunction in mouse as dhp1. The function of the human gene has notyet been determined. Transcript variants encoding differentisoforms have been noted for this gene; however, their full-lengthnature is not known.
Background Reference 1:
Lu, Y., et al. Oncogene 29(7):1041-1049(2010)
Background Reference 2:
Yang, X.C., et al. Mol. Cell. Biol. 29(1):31-42(2009)
Background Reference 3:
Kaneko, S., et al. Genes Dev. 21(14):1779-1789(2007)
Background Reference 4:
Sugiyama, N., et al. Mol. Cell Proteomics 6(6):1103-1109(2007)

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

57-673

List Size:
400 ul

List Price:

$495.00

Datasheet
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