YB1 (phospho Ser102) Antibody

CATALOG NUMBER: 79-928

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Rabbit
Species Reactivity:
Human, Mouse, Rat
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human, Mouse, Rat
Immunogen:
YB1 (phospho Ser102) antibody was raised against a peptide sequence around phosphorylation site of Serine 102 (L-R-S (p)-V-G) derived from Human YB1.
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
Western Blot: 1:500~1:1000
Specificity:
The antibody detects endogenous levels of YB1 only when phosphorylated at serine 102.
Predicted Molecular Weight:
36 kDa
Purification:
Antibodies were purified by affinity-chromatography using epitope-specific peptide.
Clonality:
Polyclonal
Isotype:
IgG
physical-state:
Liquid
Buffer:
Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration:
1 mg/mL
Storage Conditions:
Store antibody at -20°C for up to one year.
Ncbi Official Symbol:
YBX1
Additional Names:
CBF-A, NSEP1, EFI-A, MSY-1, YBX1
Protein Accession Number:
NP_004550.2
Protein Gi Number:
34098946
Ncbi Gene Id Number:
4904
Background:
YB-1 is a nuclear protein that binds to splice sites in pre-mRNA and regulates splice site selection. Binds and stabilizes cytoplasmic mRNA. Contributes to the regulation of translation by modulating the interaction between the mRNA and eukaryotic initiation factors CCAAT-containing Y-box of HLA class II genes. Component of cytoplasmic messenger ribonucleoprotein particles (mRNPs). Interacts with AKT1, SFRS9, THOC4, MSH2, XRCC5, WRN and NCL. Can bind to DNA as a homomeric form, (EFI-A)n or as a heteromeric form in association with EFI-B. Homodimer in the presence of ATP.
Background Reference 1:
Sakura H., Gene 73:499-507(1988).
Background Reference 2:
Didier D.K. Proc. Natl. Acad. Sci. U.S.A. 85:7322-7326(1988).
Background Reference 3:
Kolluri R., Nucleic Acids Res. 19:4771-4771(1991).

FOR RESEARCH USE ONLY

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Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

79-928

List Size:
0.1 mg

List Price:

$376.00

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