YY1 Antibody

CATALOG NUMBER: 60-466

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Homology:
Predicted species reactivity based on immunogen sequence: Mouse
Immunogen:
This YY1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 210-239 amino acids from the Central region of human YY1.
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
For WB starting dilution is: 1:2000
Predicted Molecular Weight:
45 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
physical-state:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
YY1
Additional Names:
Transcriptional repressor protein YY1, Delta transcription factor, INO80 complex subunit S, NF-E1, Yin and yang 1, YY-1, YY1, INO80S
Protein Accession Number:
P25490
Protein Gi Number:
3915889
Ncbi Gene Id Number:
7528
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
YY1 is a ubiquitously distributed transcription factorbelonging to the GLI-Kruppel class of zinc finger proteins. Theprotein is involved in repressing and activating a diverse numberof promoters. YY1 may direct histone deacetylases and histoneacetyltransferases to a promoter in order to activate or repressthe promoter, thus implicating histone modification in the functionof YY1.
Background Reference 1:
Yu, H., et al. Mol. Cell. Biol. 30(21):5071-5085(2010)
Background Reference 2:
Buira, S.P., et al. J. Neurochem. 115(1):283-295(2010)
Background Reference 3:
Aoyama, T., et al. J. Biol. Chem. 285(39):29842-29850(2010)
Background Reference 4:
de Nigris, F., et al. Proc. Natl. Acad. Sci. U.S.A. 107(32):14484-14489(2010)

FOR RESEARCH USE ONLY

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Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

60-466

List Size:
400 ul

List Price:

$495.00

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