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Antibody used in WB on Human Lung at 0.2-1 ug/ml.
Antibody used in WB on Human Lung at 0.2-1 ug/ml.

ZFP36 Antibody

CATALOG NUMBER: 28-842

Clonality:
Polyclonal
Tested Applications:
ELISA, WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Immunogen:
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human ZFP36.
Conjugate:
Unconjugated
Tested Applications:
ELISA, WB
Application Note:
ZFP36 antibody can be used for detection of ZFP36 by ELISA at 1:312500. ZFP36 antibody can be used for detection of ZFP36 by western blot at 0.25 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Positive Control 1:
Cat. No. XBL-10410 - Fetal Lung Tissue Lysate
Predicted Molecular Weight:
34 kDa
Purification:
Antibody is purified by peptide affinity chromatography method.
Clonality:
Polyclonal
physical-state:
Liquid
Buffer:
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Concentration:
batch dependent
Storage Conditions:
For short periods of storage (days) store at 4°C. For longer periods of storage, store ZFP36 antibody at -20°C. As with any antibody avoid repeat freeze-thaw cycles.
Ncbi Official Symbol:
ZFP36
Additional Names:
ZFP36, TTP, G0S24, GOS24, TIS11, NUP475, zfp-36, RNF162A
Protein Accession Number:
NP_003398
Protein Gi Number:
393539038
Ncbi Gene Id Number:
7538
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
ZFP36 is a probable regulatory protein with a novel zinc finger structure involved in regulating the response to growth factors. Knockdown of ZFP36 increased both cognate macrophage gene mRNAs and inflammatory tumor necrosis factor protein release. Overexpression of ZFP36 resulted in decreased levels of the same genes supporting its role in regulating macrophage gene expression. Multiple phosphorylation sites in ZFP36 in mammalian cells were reported. ZFP36 can be phosphorylated by JNK as well as by the other members of the greater MAP kinase family. Gene expression profiling predicts clinical outcome of prostate cancer. Inappropriate ZFP36 production may be one factor that contributes to higher rheumatoid arthritis disease activity.
Background Reference 1:
Cao, H., et al., (2006) Biochem. J. 394 (PT 1), 285-297.

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
This product is for research use only.

CATALOG NUMBER:

28-842

List Size:
100 ul

List Price:

$519.00

Datasheet
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