Trial Size

ZIP11 Antibody

CATALOG NUMBER: 5001

Clonality:
Polyclonal
Tested Applications:
ELISA, IHC-P, WB
Host Species:
Rabbit
Species Reactivity:
Human, Mouse, Rat
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human, Mouse, Rat
Homology:
Predicted species reactivity based on immunogen sequence: Bovine: (86%)
Immunogen:
ZIP11 antibody was raised against a 15 amino acid synthetic peptide near the center of the human ZIP11.
The immunogen is located within amino acids 130 - 180 of ZIP11.
Conjugate:
Unconjugated
Tested Applications:
ELISA, IHC-P, WB
Application Note:
ZIP11 antibody can be used for detection of ZIP11 by Western blot at 1 - 2 μg/mL. Antibody can also be used for immunohistochemistry starting at 2.5 μg/mL.
Antibody validated: Western Blot in mouse samples and Immunohistochemistry in mouse samples. All other applications and species not yet tested.
Specificity:
This antibody will not cross-react with the zinc transporter ZIP10.
Positive Control 1:
Cat. No. 1405 - Mouse Kidney Tissue Lysate
Purification:
ZIP11 Antibody is affinity chromatography purified via peptide column.
Clonality:
Polyclonal
Isotype:
IgG
physical-state:
Liquid
Buffer:
ZIP11 Antibody is supplied in PBS containing 0.02% sodium azide.
Concentration:
1 mg/mL
Storage Conditions:
ZIP11 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
SLC39A11
Additional Names:
ZIP11 Antibody: ZIP11, C17orf26, ZIP11, Zinc transporter ZIP11, Solute carrier family 39 member 11, ZIP-11
Protein Accession Number:
EAW89107
Protein Gi Number:
119609513
Ncbi Gene Id Number:
201266
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
ZIP11 Antibody: ZIP11, also known as Slc39A11, is a member of the broader ZIP family of multi-transmembrane domain metal ion transporters. Zinc is an essential ion for cells and plays significant roles in the growth, development, and differentiation. Members of the ZIP family generally transport metal ions from the cell exterior or lumen of intracellular organelles into the cytoplasm, as opposed to the ZnT (SLC30) family of zinc transporters that serve to reduce intracellular zinc availability by promoting zinc efflux from cells or into intracellular vesicles. At least three isoforms of ZIP11 are known to exist.
Background Reference 1:
Eide DJ. The SLC39 family of metal ion transporters. Pflugers Arch.2004; 447:796-800.
Background Reference 2:
Taylor KM and Nicohlson RI. The LZT proteins; the LIV-1 subfamily of zinc transporters. Biochim. Biophys. Acta.2003; 1611:16-30.
Background Reference 3:
Liuzzi JP and Cousins RJ. Mammalian zinc transporters. Annu. Rev. Nutr.2004; 24:151-72.

FOR RESEARCH USE ONLY

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Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

5001

List Size:
0.02 mg, 0.1 mg

List Price:

Price range: $99.00 through $445.00

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