ZNF76 Antibody

CATALOG NUMBER: 28-844

Clonality:
Polyclonal
Tested Applications:
ELISA, WB
Host Species:
Rabbit
Species Reactivity:
Dog, Human, Mouse, Rat
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Dog, Human, Mouse, Rat
Immunogen:
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human ZNF76.
Conjugate:
Unconjugated
Tested Applications:
ELISA, WB
Application Note:
ZNF76 antibody can be used for detection of ZNF76 by ELISA at 1:312500. ZNF76 antibody can be used for detection of ZNF76 by western blot at 1.25 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Positive Control 1:
Cat. No. 1211 - HepG2 Cell Lysate
Predicted Molecular Weight:
62 kDa
Purification:
Antibody is purified by protein A chromatography method.
Clonality:
Polyclonal
physical-state:
Liquid
Buffer:
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Concentration:
batch dependent
Storage Conditions:
For short periods of storage (days) store at 4°C. For longer periods of storage, store ZNF76 antibody at -20°C. As with any antibody avoid repeat freeze-thaw cycles.
Ncbi Official Symbol:
ZNF76
Additional Names:
ZNF76, ZNF523, Zfp523, D6S229E
Protein Accession Number:
NP_003418
Protein Gi Number:
21361146
Ncbi Gene Id Number:
7629
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
ZNF76 belongs to the krueppel C2H2-type zinc-finger protein family. ZNF76 is a general transcription repressor targeting TATA-binding protein (TBP), through a process regulated by sumoylation. ZNF76 interacts with TBP through both its N and C termini, and both regions are required for ZNF76 to exert its inhibitory function on p53-mediated transactivation. As a TBP-interacting transcriptional modulator, ZNF76 is also regulated by alternative splicing.
Background Reference 1:
Zheng, G. (2006) Biochem. Biophys. Res. Commun. 339 (4), 1069-1075.

FOR RESEARCH USE ONLY

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Disclaimer:
This product is for research use only.

CATALOG NUMBER:

28-844

List Size:
100 ul

List Price:

$473.00

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