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Western blot analysis in HepG2 cell line lysates (35ug/lane).
Western blot analysis in HepG2 cell line lysates (35ug/lane).

ZNRF1 Antibody

CATALOG NUMBER: 58-699

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Homology:
Predicted species reactivity based on immunogen sequence: Mouse
Immunogen:
This ZNRF1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 59-86 amino acids from the Central region of human ZNRF1.
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
For WB starting dilution is: 1:1000
Predicted Molecular Weight:
24 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
physical-state:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
ZNRF1
Additional Names:
E3 ubiquitin-protein ligase ZNRF1, 632-, Nerve injury-induced gene 283 protein, Zinc/RING finger protein 1, ZNRF1, NIN283
Protein Accession Number:
Q8ND25
Protein Gi Number:
126253846
Ncbi Gene Id Number:
84937
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
In a study identifying genes in rat that are upregulatedin response to nerve damage, a gene which is highly expressed inganglia and in the central nervous system was found. The proteinencoded by the rat gene contains both a zinc finger and a RINGfinger motif and is localized in the endosome/lysosome compartment,indicating that it may be involved in ubiquitin-mediated proteinmodification. The protein encoded by this human gene is highlysimilar in sequence to that encoded by the rat gene. [provided byRefSeq].
Background Reference 1:
Dastani, Z., et al. Eur. J. Hum. Genet. 18(3):342-347(2010)
Background Reference 2:
Yoshida, K., et al. Biochem. Biophys. Res. Commun. 389(3):506-511(2009)
Background Reference 3:
Markson, G., et al. Genome Res. 19(10):1905-1911(2009)
Background Reference 4:
van Wijk, S.J., et al. Mol. Syst. Biol. 5, 295 (2009) :

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

58-699

List Size:
400 ul

List Price:

$495.00

Datasheet
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