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Western blot analysis in NCI-H460 cell line lysates (35ug/lane).
Western blot analysis in NCI-H460 cell line lysates (35ug/lane).

RLN2 Antibody

CATALOG NUMBER: 60-368

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Immunogen:
This RLN2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 139-165 amino acids from the C-terminal region of human RLN2.
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
For WB starting dilution is: 1:1000
Predicted Molecular Weight:
21 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
Physical State:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
RLN2
Additional Names:
Prorelaxin H2, Relaxin B chain, Relaxin A chain, RLN2
Protein Accession Number:
P04090
Protein Gi Number:
132281
Ncbi Gene Id Number:
6019
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
Relaxins are known endocrine and autocrine/paracrinehormones, belonging to the insulin gene superfamily. In the humanthere are three non-allelic relaxin genes, RLN1, RLN2 and RLN3.RLN1 and RLN2 share high sequence homology. The active form of theencoded protein consists of an A chain and a B chain but theircleavage sites are not definitely described yet. Relaxin isproduced by the ovary, and targets the mammalian reproductivesystem to ripen the cervix, elongate the pubic symphysis andinhibit uterine contraction. It may have additional roles inenhancing sperm motility, regulating blood pressure, controllingheart rate and releasing oxytocin and vasopressin. There are twoalternatively spliced transcript variants encoding differentisoforms described for this gene.
Background Reference 1:
Davila, S., et al. Genes Immun. 11(3):232-238(2010)
Background Reference 2:
Vogel, I., et al. In Vivo 23(6):1005-1009(2009)
Background Reference 3:
Dschietzig, T., et al. Regul. Pept. 155 (1-3), 163-173 (2009) :
Background Reference 4:
Mookerjee, I., et al. FASEB J. 23(4):1219-1229(2009)

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

60-368

List Size:
400 ul

List Price:

$495.00

Datasheet
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