VISTA/B7-H5/platelet receptor Gi24 is a single-pass type I membrane protein located at the cell surface. It is an immunoregulatory receptor which can inhibit T-cell response and may promote differentiation of embryonic stem cells, by inhibiting the BMP4 signaling pathway. The protein can be cleaved by MMP14, and stimulate MMP14-mediated MMP2 activation.
ProSci’s monoclonal immune checkpoint antibodies made to improve in vivo studies. Unlike antibodies developed using proteins made in yeast or bacteria, these VISTA antibodies are developed with antigens expressed in mammalian cell lines, giving the most native post-translational modifications to the protein. They are guaranteed to work for their tested applications.
Sets consist of 20µg aliquots of several mouse monoclonal antibodies with different binding features allowing for selection of the best clone for your application.
| Product Set | Contents |
|---|---|
| Risk-Free VISTA Set (RF16070) | RF16071, RF16072, RF16073, RF16074 |
ProSci’s Risk-Free VISTA antibodies are rigorously tested and guaranteed to work for their designated applications. VISTA antibodies were raised against the extracellular domain of human VISTA.
KEY:
| Cat. No. | Product Type | Source |
|---|---|---|
| RF10001-03 | Positive Control (Tissue Lysate) | Human Spleen |
| RF10001-02 | Negative Control (Cell Lysate) | HEK293 |
| RF10002-02 | Positive Control (Tissue Slides) | Human Spleen |
| RF10002-03 | Negative Control (Cell Slides) | HEK293 |
| Cat. No. | Name | Host | Clonality | Applications |
|---|---|---|---|---|
| 8695 | VISTA Antibody | Rabbit | Polyclonal | ELISA, IF, IHC-P, WB |
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