CD80, also known as B7-1, is a type I membrane protein that is a member of the immunoglobulin superfamily that is expressed by antigen-presenting cells. Like the related protein CD86, this protein is expressed by antigen-presenting cells and is the ligand for CD28 and CTLA-4 at the cell surface of T cells. Binding of this protein with CD28 antigen is a costimulatory signal for activation of the T-cell and induces T-cell proliferation and cytokine production.
ProSci’s monoclonal immune checkpoint antibodies made to improve in vitro studies. Unlike antibodies developed using proteins made in yeast or bacteria, these CD80 antibodies are developed with antigens expressed in mammalian cell lines, giving the most native post-translational modifications to the protein. They are guaranteed to work for their tested applications
Sets consist of 20µg aliquots of several mouse monoclonal antibodies with different binding features allowing for selection of the best clone for your application.
ProSci’s Risk-Free CD80 antibodies are rigorously tested and guaranteed to work for their designated applications. Mouse monoclonal CD80 antibodies were raised against the extracellular domain of human CD80.
| Cat. No. | Product Type | Source |
|---|---|---|
| RF10001-06 | Positive Control (Cell Lysate) | Raji |
| RF10001-04 | Positive Control (Tissue Lysate) | Human Tonsil |
| RF10002-04 | Positive Control (Cell Slides) | Raji |
| RF10002-02 | Negative Control (Cell Slides) | HEK293 |
| Cat. No. | Name | Host | Clonality | Applications |
|---|---|---|---|---|
| 8679 | CD80 Antibody | Rabbit | Polyclonal | ELISA, IF, IHC-P, WB |
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