ProSci Incorporated is Proud to announce that it has been selected as the 2022 Bioz Stars Award Winner in the COVID-19 Category. Celebrating Excellence: ProSci Awarded ‘Rapid Star Winner’ – November 14, 2022 – San Diego, California, United States –...
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What is an inflammasome? An inflammasome is a formation of danger-sensing proteins when a cell becomes infected or damaged and is typically there to regulate the activation of caspase-1 and activate inflammation when host proteins create infectious microbes and molecules....
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https://www.cell.com/cell/fulltext/S0092-8674(22)00651-1 Bone Marrow Hematopoiesis Drives Multiple Sclerosis Progression – Multiple sclerosis (MS) is categorized as an autoimmune disease where T cells attack the central nervous system and cause inflammation in the brain. New evidence shows that the bone marrow is...
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As of May 2022, a highly contagious influenza virus continues to wreak havoc on domestic bird flocks across the United States. Millions of chickens and other fowl are dying or being killed to stop the spread of an HPAI (highly...
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There are many ways single domain antibodies (sdAbs) — also known as Nanobodies™, VHH antibodies, and camelid antibodies are superior to conventional antibodies. Read on to find out how these unique antibodies can enhance your research. The Advantages of Single...
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SARS-CoV-2 protease Mpro (NSP5), a key to COVID-19 therapy? – Pfizer announced promising clinical trials for their drug Paxlovid (Owen et al., 2021), an inhibitor of the main SARS-CoV-2 protease, Mpro (3CLpro, NSP5). In addition to being the main SARS-CoV-2...
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ProSci applauds the work described in two recent publications regarding the synthesis, production, and utility of SARS-CoV-2 virus-like particles (VLPs). SARS-CoV-2 Virus-like Particles (VLPs) – Naskalska et al. (2021) (DOI: 10.3389/fmicb.2021.732998) created recombinant His-tagged forms of SARS-CoV-2 structural proteins that...
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Pre-activated antiviral innate immunity in the upper airways controls early SARS-CoV-2 infection in children Loske et al. (2021) https://www.nature.com/articles/s41587-021-01037-9 The recent study by Loske et al (2021) investigated why children have reduced severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection...
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SARS-CoV-2 (COVID-19) Mutations – As viruses create more of themselves within a host, they are prone to copying errors. These mutations or recombinations are single-point changes in the virus’ genetic code. Most of these changes do nothing, but others can...
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The Effect of SAR-CoV-2 Vaccine Lasts At Least 4 Months – N Engl J Med reported the durability of immunity response of SARS-CoV-2 vaccine, mRNA-1273 (Moderna). The data was from 34 healthy adults with two vaccine injections. They have performed...
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