The Importance of Quality Immuno-oncology Antibody Reagents In Studying Immune Checkpoint Inhibitors These days, it’s tough to mention cancer without also mentioning the novel class of cancer-fighting immuno-oncology therapeutics called immune checkpoint inhibitors. These transformative drugs have extended the life...
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August 2017: The Antibody Update – Zika has run its course for now Herd immunity to Zika virus in American populations is reported to have caused a tremendous decline in the number of cases this year. There was only one...
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Many scientists expressing interest in single domain antibodies have been curious about the best ways to detect single domain antibodies with in vitro assays. When detecting typical IgG antibodies, secondary antibodies with conjugated enzymes or fluorophores are used for detection...
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May 2017: The Antibody Update – Inhibition of Indolamine 2, 3 Dioxygenase (IDO) for Cancer Immunotherapy Researchers have found that a drug which inhibits IDO can increase the effectiveness of cancer immunotherapy. Epacadostat, which is an IDO inhibitor, successfully increased...
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Why Are Antibodies Produced in the Body? – Antibody Production in Human Body serves three primary roles in the immune system: neutralization, opsonization, and complement protein activation. These essential functions protect the body from harmful pathogens, ensuring the immune system...
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April 2017: The Antibody Update Frog-derived Hemagglutinin-Bearing Flu Antiviral An epidermal host defense peptide from the South Indian frog named urumin is virucidal for H1 hemagglutinin-bearing human influenza A viruses. It was demonstrated that this peptide destroyed influenza virions. It...
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When selecting an antigen to use for your project, the considerations required can be overwhelming. We at ProSci want your antibody project to run smoothly so your work can be done without interruption. For us to deliver high performance antibodies,...
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Caffeine is an Indirect Anti-Inflammatory Drug Interleukin-1β production is regulated by inflammasomes, a very large protein complex commonly associated with inflammation and pyroptosis. As the human body ages and accumulates metabolites, the inflammasome interacts with them and is primed for...
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February 2017: The Antibody Update – Epidermal Levels of Staphylococcus Aureus Are Affected by a Peptide Produced by Other Skin Dwelling Bacteria Staphylococcus aureus is common to many of people’s skin microbiome, and is generally harmless; however, in high population...
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Pairs of proteins that act as T-cell co-signaling receptors are called immune checkpoints. These cell surface receptors can send positive or negative signals to T cells, instigating a response from the immune system to either stimulate the immune system against...
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