April 2017: The Antibody Update Frog-derived Hemagglutinin-Bearing Flu Antiviral An epidermal host defense peptide from the South Indian frog named urumin is virucidal for H1 hemagglutinin-bearing human influenza A viruses. It was demonstrated that this peptide destroyed influenza virions. It...
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When selecting an antigen to use for your project, the considerations required can be overwhelming. We at ProSci want your antibody project to run smoothly so your work can be done without interruption. For us to deliver high performance antibodies,...
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Caffeine is an Indirect Anti-Inflammatory Drug Interleukin-1β production is regulated by inflammasomes, a very large protein complex commonly associated with inflammation and pyroptosis. As the human body ages and accumulates metabolites, the inflammasome interacts with them and is primed for...
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February 2017: The Antibody Update – Epidermal Levels of Staphylococcus Aureus Are Affected by a Peptide Produced by Other Skin Dwelling Bacteria Staphylococcus aureus is common to many of people’s skin microbiome, and is generally harmless; however, in high population...
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Pairs of proteins that act as T-cell co-signaling receptors are called immune checkpoints. These cell surface receptors can send positive or negative signals to T cells, instigating a response from the immune system to either stimulate the immune system against...
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January 2017: The Antibody Update – Mitigating the Reproducibility Crisis in Cancer Drug Research Reproducibility has been highlighted as one of the main problems when validating cancer research. Scientists with the The Reproducibility Project have opted to begin pragmatically reviewing...
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T-cell Activation: The Purpose of CD28, CTLA-4, and CD80/CD86 – A Guide to CD28, CTLA-4, and CD80/CD86 Interaction and Signaling Immune checkpoint receptors like CD28 and CTLA-4 have been of great interest in the research of cancer immunotherapy. These receptors...
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Merck’s Ebola Vaccine is 100% Effective December 2016: The Antibody Update – An extremely effective Ebola virus vaccine created by Merck was recently tested in Guinea with 100% effectiveness. Though the vaccine is late for the worst part of the...
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in China Perform First Injection of CRISPR Modified Cells into a Person Use of CRISPR-Cas9 in human cells for treatment of disease has been a controversial topic amongst scientists since the discovery of the powerful gene editing tool. In this...
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Bacterial vs. Mammalian Expression Systems – Expressing recombinant antibodies can be done in all kinds of systems. Many different cell lines can be used for expressing antibodies, including mammalian cells like HEK293 or CHO, or even yeast, plant or insect...
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