ProSci aims to help researchers with difficult antigen targets We take pride in being able to make challenging antibodies, including anti-idiotypic antibodies, antibodies against small molecules, or even antibodies against modified proteins. With over 20,000 completed projects, we can create...
Share this post:
[siteorigin_widget class=”SiteOrigin_Widget_Image_Widget”][/siteorigin_widget] Polyclonal vs Monoclonal vs Recombinant Antibodies While simple in principle, antibodies are deceivingly complex in structure and to produce. There are key distinctions between polyclonal, monoclonal, and recombinant antibody production that are important to consider when designing a...
Share this post:
What are Proprotein convertases? SARS-CoV-2 Cleavage – Proprotein convertases (PC) are comprised of 9 serine secretory proteases that regulate biological processes involved in both healthy and disease states. They are responsible for activating precursor proteins and cell surface glycoproteins of...
Share this post:
Introduction to the 5 A’s of Antibody Development – Antibody development is a multi-faceted process comprised of 5 major elements: Antigen, Adjuvant, Animal, Antibody, and Application. The process is cyclical beginning with the target you wish to develop antibodies against...
Share this post:
2019 Novel Coronavirus SARS-COV-2: The Emergence of COVID-19 At the end of 2019, Chinese authorities officially notified the World Health Organization about mysterious pneumonia infections. A week later, scientists identified a novel coronavirus with the full genome of SARS-COV-2 as...
Share this post:
The Importance of Quality Immuno-oncology Antibody Reagents In Studying Immune Checkpoint Inhibitors These days, it’s tough to mention cancer without also mentioning the novel class of cancer-fighting immuno-oncology therapeutics called immune checkpoint inhibitors. These transformative drugs have extended the life...
Share this post:
August 2017: The Antibody Update – Zika has run its course for now Herd immunity to Zika virus in American populations is reported to have caused a tremendous decline in the number of cases this year. There was only one...
Share this post:
Many scientists expressing interest in single domain antibodies have been curious about the best ways to detect single domain antibodies with in vitro assays. When detecting typical IgG antibodies, secondary antibodies with conjugated enzymes or fluorophores are used for detection...
Share this post:
May 2017: The Antibody Update – Inhibition of Indolamine 2, 3 Dioxygenase (IDO) for Cancer Immunotherapy Researchers have found that a drug which inhibits IDO can increase the effectiveness of cancer immunotherapy. Epacadostat, which is an IDO inhibitor, successfully increased...
Share this post:
Why Are Antibodies Produced in the Body? – Antibody Production in Human Body serves three primary roles in the immune system: neutralization, opsonization, and complement protein activation. These essential functions protect the body from harmful pathogens, ensuring the immune system...
Share this post:
