Cytokine Storm and COVID-19 What is Cytokine Storm? – Garnering mass attention due to the COVID-19 pandemic caused by the SARS-CoV-2 virus, the “cytokine storm” has been observed for decades. Cytokine storm refers to the overproduction of cytokines by the...
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SARS-CoV-2 (COVID-19) Mutations – As viruses create more of themselves within a host, they are prone to copying errors. These mutations or recombinations are single-point changes in the virus’ genetic code. Most of these changes do nothing, but others can...
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The Effect of SAR-CoV-2 Vaccine Lasts At Least 4 Months – N Engl J Med reported the durability of immunity response of SARS-CoV-2 vaccine, mRNA-1273 (Moderna). The data was from 34 healthy adults with two vaccine injections. They have performed...
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Rabbit Monoclonal Antibodies Why choose rabbit monoclonal antibodies for your antibody development process? Rabbits provide strategic benefits over mice when it comes to producing monoclonal antibodies. The rabbit spleen contains more B cells than the mouse spleen, as the rabbit...
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Cell Paper: Genome-wide CRISPR Screen Reveal Host Factors Critical for SARS-CoV-2 Infection ProSci Incorporated’s ACE2 Antibody Published in Cell: ACE2 Rabbit Polyclonal Antibody for Western Blotting – COVID-19 (SARS-CoV-2) is a major public health threat with more than 1,200,000 deaths...
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ProSci aims to help researchers with difficult antigen targets We take pride in being able to make challenging antibodies, including anti-idiotypic antibodies, antibodies against small molecules, or even antibodies against modified proteins. With over 20,000 completed projects, we can create...
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[siteorigin_widget class=”SiteOrigin_Widget_Image_Widget”][/siteorigin_widget] Polyclonal vs Monoclonal vs Recombinant Antibodies While simple in principle, antibodies are deceivingly complex in structure and to produce. There are key distinctions between polyclonal, monoclonal, and recombinant antibody production that are important to consider when designing a...
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What are Proprotein convertases? SARS-CoV-2 Cleavage – Proprotein convertases (PC) are comprised of 9 serine secretory proteases that regulate biological processes involved in both healthy and disease states. They are responsible for activating precursor proteins and cell surface glycoproteins of...
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Introduction to the 5 A’s of Antibody Development – Antibody development is a multi-faceted process comprised of 5 major elements: Antigen, Adjuvant, Animal, Antibody, and Application. The process is cyclical beginning with the target you wish to develop antibodies against...
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2019 Novel Coronavirus SARS-COV-2: The Emergence of COVID-19 At the end of 2019, Chinese authorities officially notified the World Health Organization about mysterious pneumonia infections. A week later, scientists identified a novel coronavirus with the full genome of SARS-COV-2 as...
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