https://www.cell.com/cell/fulltext/S0092-8674(22)00651-1 Bone Marrow Hematopoiesis Drives Multiple Sclerosis Progression – Multiple sclerosis (MS) is categorized as an autoimmune disease where T cells attack the central nervous system and cause inflammation in the brain. New evidence shows that the bone marrow is...
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Intro to the Pseudovirus It has been two years since the outbreak of coronavirus disease 2019 (COVID-19). Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) was identified as the cause of the pandemic and has only gotten more complex for scientists...
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As of May 2022, a highly contagious influenza virus continues to wreak havoc on domestic bird flocks across the United States. Millions of chickens and other fowl are dying or being killed to stop the spread of an HPAI (highly...
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The monkeypox virus that has been reported in mainstream and scientific news is part of the Orthopoxvirus genus that closely resembles smallpox (variola) virus. (1) The genetic code of monkeypox is similar enough to smallpox that known vaccines, such as...
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Breaking Research News: Study Shows Young CSF made old mice younger – A recent study published in Nature (May 11, 2022) displayed that infusion of young CSF (cerebral spinal fluid) into the brains of aged mice improves their memory function....
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In this blog, ProSci will take you through the advantages of single domain antibodies—also known as Nanobodies™, VHH antibodies, and camelid antibodies—and the process ProSci uses to develop high-performing antibodies. Single Domain Antibodies (sdAbs) from the camelid family are exciting...
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New SARS-CoV-2 Recombinant Virus Lineages – Three SARS-CoV-2 recombinant lineages have been designated by Pangolin as of March 2022, two a combination of Delta and BA.1 (designated XD and XF), and the third a combination of Omicron BA.1 and Omicron...
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There are many ways single domain antibodies (sdAbs) — also known as Nanobodies™, VHH antibodies, and camelid antibodies are superior to conventional antibodies. Read on to find out how these unique antibodies can enhance your research. The Advantages of Single...
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SARS-CoV-2 protease Mpro (NSP5), a key to COVID-19 therapy? – Pfizer announced promising clinical trials for their drug Paxlovid (Owen et al., 2021), an inhibitor of the main SARS-CoV-2 protease, Mpro (3CLpro, NSP5). In addition to being the main SARS-CoV-2...
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ProSci applauds the work described in two recent publications regarding the synthesis, production, and utility of SARS-CoV-2 virus-like particles (VLPs). SARS-CoV-2 Virus-like Particles (VLPs) – Naskalska et al. (2021) (DOI: 10.3389/fmicb.2021.732998) created recombinant His-tagged forms of SARS-CoV-2 structural proteins that...
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